The development of the science of economics is closely linked to the structure of capitalism. Even though ancient and medieval thinkers had already stated a certain number of ideas in this domain, the science of economics, in the modern sense of the word, did not truly begin until the 17th Century and the early 18th Century. At that time the methodology for research in the natural sciences was developed, and the first scientific academies and societies were founded (England, France, Prussia, (...) Russia). The initial step in the development of the science of economics occurred in conjunction with this process. Moreover, the ideas of the first economists were, as a general rule, centered on the practical problems and needs of the State. And in that period the prevalent state structure in Europe was the absolute monarchy. Consequently, the first economists were, for the most part, counsellors to the sovereign, authors of studies and reports containing a variety of proposals regarding economic policy. With regard to a great many distinguished economists of the 17th and 18th Centuries, we can speak of them being “men of proposals”. (shrink)

Motivation: There is an ongoing search for definitive and reliable biomarkers to forecast or predict imminent seizure onset, but to date most research has been limited to EEG with sampling rates <1,000 Hz. High-frequency oscillations have gained acceptance as an indicator of epileptic tissue, but few have investigated the temporal properties of HFOs or their potential role as a predictor in seizure prediction. Here we evaluate time-varying trends in preictal HFO rates as a potential biomarker of seizure prediction.Methods: HFOs were (...) identified for all interictal and preictal periods with a validated automated detector in 27 patients who underwent intracranial EEG monitoring. We used LASSO logistic regression with several features of the HFO rate to distinguish preictal from interictal periods in each individual. We then tested these models with held-out data and evaluated their performance with the area-under-the-curve of their receiver-operating curve. Finally, we assessed the significance of these results using non-parametric statistical tests.Results: There was variability in the ability of HFOs to discern preictal from interictal states across our cohort. We identified a subset of 10 patients in whom the presence of the preictal state could be successfully predicted better than chance. For some of these individuals, average AUC in the held-out data reached higher than 0.80, which suggests that HFO rates can significantly differentiate preictal and interictal periods for certain patients.Significance: These findings show that temporal trends in HFO rate can predict the preictal state better than random chance in some individuals. Such promising results indicate that future prediction efforts would benefit from the inclusion of high-frequency information in their predictive models and technological architecture. (shrink)

Over recent decades International Relations scholars have investigated norm dynamics processes at some length, with the norm entrepreneur concept having become a common reference point in the literature. The focus on norm entrepreneurs has, however, resulted in a bias towards investigating the agents and processes of successful normative change. This book challenges this inherent bias by explicitly focusing on those who resist normative change - norm antipreneurs. The utility of the norm antipreneur concept is explored through a series of case (...) studies encompassing a range of issue areas and contributed by a mix of well-known and emergent scholars of norm dynamics. In examining the complexity of norm resistance, particular attention is paid to the nature and intent of the actors involved in norm-contestation, the sites and processes of resistance, the strategies and tactics antipreneurs deploy to defend the values and interests they perceive to be threatened by the entrepreneurs, and whether it is the entrepreneurs or the antipreneurs who enjoy greater inherent advantages. This text will therefore be of interest to scholars and students of International Relations, International Law, Political Science, Sociology and History. ". (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

State Medical Boards (SMBs) can take severe disciplinary actions (e.g., license revocation or suspension) against physicians who commit egregious wrongdoing in order to protect the public. However, there is noteworthy variability in the extent to which SMBs impose severe disciplinary action. In this manuscript, we present and synthesize a subset of 11 recommendations based on findings from our team’s larger consensus-building project that identified a list of 56 policies and legal provisions SMBs can use to better protect patients from egregious (...) wrongdoing by physicians. (shrink)

What sorts of things are there in the world? Clearly enough, there are concrete, material things; but are there other things too, perhaps nonconcrete or non-material things? Some people believe that there are such things, which are often called abstract ; purported examples of such objects include numbers, properties, possible but non-actual states of affairs, propositions, and sets. Following a long-standing tradition, I shall describe persons who believe that there are abstract objects as ‘platonists’. In this paper, I shall not (...) directly address the plausibility of platonism, as compared with its rivals; instead, I shall confine my attention to one way in which some people have tried to combine platonism and theism. More specifically, I shall concentrate upon the claim that abstract objects depend upon God ontologically ; I shall argue that platonistic theists should reject DEP in favour of the claim that abstract objects exist independently of God . In order to evaluate the relative merits of DEP versus IND, it will be helpful to examine in some detail a particular articulation of DEP. When it comes to recent work on DEP, we can do no better in this regard than to examine the recent work of Thomas V. Morris and Christopher H. Menzel. According Morris and Menzel, there is a sense in which God literally creates such abstracta through engaging in intellective activities. (shrink)

The modern legal and ethical movement against traditional welfare paternalism in medical decision-making extends to how decisions are made for patients lacking decisional capacity, prioritising surrogates’ judgment about what patients would have decided over even their best interests. In England and Wales, the Mental Capacity Act 2005 follows this trend of prioritising the patient’s prior wishes, values and beliefs but the dominant interpretation in life-sustaining treatment cases does so by in effect calling those values the ‘best interests’ of the patient (...) and focusing nearly exclusively on the ‘subjective’ viewpoint of the patient. In this article, we examine the recent Court of Protection judgment inBarnsley Hospitals NHS Foundation Trust v MSP[2020] EWCOP 26, which adhered closely to this approach, to suggest that it could have unexpected negative consequences. These include insufficient information gathering about and attention to patients’ objective medical interests, inadequacy of the evidentiary standard used for the substituted decision-making and, in some cases, even prioritising a surrogate’s current substituted judgment over the potential for an actual judgment by the patient. (shrink)

Presents a plethora of approaches to developing human potential in areas not conventionally addressed. Organized in two parts, this international collection of essays provides viable educational alternatives to those currently holding sway in an era of high-stakes accountability.

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

Rights of Women attracted much UK media attention in late 2014 by bringing a judicial review that challenged the reduced provisions for family law legal aid available for victims of domestic violence: R v The Lord Chancellor and Secretary of State for Justice [2015] EWHC 35. In June 2015, within Rights of Women’s 40th anniversary year, Hannah Camplin interviewed the organisation’s Director Emma Scott about the decision to bring the judicial review, the advantages and challenges of the judicial review (...) process, and the experience of strategic litigation within the context of Rights of Women’s long history of campaigning for women’s rights. What emerged is a portrait of a feminist organisation in 2015, and, in a fast changing political and financial landscape, the dual importance of collaborative working and the need for flexibility in service provision and campaigning tools. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Editorial StatementScott Gelfand, CoeditorOnce per year The Pluralist publishes an issue devoted exclusively to values. This year’s issue contains articles on a variety of related topics, including the difference between strong and weak pluralism in classroom communities; curing ills facing today’s college students with the aid of Aquinas’s ethical theory; the Golden Rule and virtue ethics; advance directives and psychological accounts of identity; Judith Butler, the personal, the political (...) and theological discourse; George Herbert Mead, social conceptions of self and moral reasoning; William James’s ideas about militarism applied to American foreign policy since 1945; and the philosophical roots of Martin Luther King, Jr.’s, important moral ideal of a beloved community. We hope you will find this selection provocative and informative. [End Page v]Scott Gelfand, CoeditorOklahoma State UniversityCopyright © 2009 Board of Trustees of the University of Illinois... (shrink)

We extend the results of Laver on using inverse limits to reflect large cardinals of the form, there exists an elementary embedding Lα → Lα. Using these inverse limit reflection embeddings directly and by broadening the collection of U-representable sets, we prove structural results of L under the assumption that there exists an elementary embedding j : L → L. As a consequence we show the impossibility of a generalized inverse limit X-reflection result for X ⊆ Vλ+1, thus focusing the (...) study of L generalizations on L. (shrink)

Scholarly attempts to analyze the history of science sometime suffer from an imprecise use of terms. In order to understand accurately how science has developed and from where it draws its roots, researchers should be careful to recognize that epistemic regimes change over time and acceptable forms of knowledge production are contingent upon the hegemonic discourse informing the epistemic regime of any given period. In order to understand the importance of this point, I apply the techniques of historical epistemology to (...) an analysis of the place of the study of astrology in the medieval and early modern periods alongside a discussion of the “language games” of these period as well as the role of the “archeology of knowledge” in uncovering meaning in our study of the past. In sum, I argue that the term “science” should never be used when studying approaches to knowledge formation prior to the seventeenth century. (shrink)

A correction has been made to: Bar, Roi. The Forgotten Phenomenology: “Enactive Perception” in the Eyes of Husserl and Merleau-Ponty. Journal of French and Francophone Philosophy, v. 28, n. 1, p. 53-72, june 2020.The incorrect abstract was included with the original publication of DOI 10.5195/jffp.2020.928The original article has been updated to reflect this change.

Introduction to the Two Volumes xi PART ONE: G. E. MOORE ON ETHICS, EPISTEMOLOGY, AND PHILOSOPHICAL ANALYSIS 1 CHAPTER 1 Common Sense and Philosophical Analysis 3 CHAPTER 2 Moore on Skepticism, Perception, and Knowledge 12 CHAPTER 3 Moore on Goodness and the Foundations of Ethics 34 CHAPTER 4 The Legacies and Lost Opportunities of Moore’s Ethics 71 Suggested Further Reading 89 PART TWO: BERTRAND RUSSELL ON LOGICAL AND LINGUISTIC ANALYSIS 91 CHAPTER 5 Logical Form, Grammatical Form, and the Theory of (...) Descriptions 93 CHAPTER 6 Logic and Mathematics: The Logicist Reduction 132 CHAPTER 7 Logical Constructions and the External World 165 CHAPTER 8 Russell’s Logical Atomism 182 Suggested Further Reading 194 PART THREE: LUDWIG WITTGENSTEIN’S TRACTATUS 195 CHAPTER 9 The Metaphysics of the Tractatus 197 CHAPTER 10 Meaning, Truth, and Logic in the Tractatus 214 CHAPTER 11 The Tractarian Test of Intelligibility and Its Consequences 234 Suggested Further Reading 254 PART FOUR: LOGICAL POSITIVISM, EMOTIVISM, AND ETHICS 255 CHAPTER 12 The Logical Positivists on Necessity and Apriori Knowledge 257 CHAPTER 13 The Rise and Fall of the Empiricist Criterion of Meaning 271 CHAPTER 14 Emotivism and Its Critics 300 CHAPTER 15 Normative Ethics in the Era of Emotivism: The Anticonsequentialism of Sir David Ross 320 Suggested Further Reading 346 PART FIVE: THE POST-POSITIVIST PERSPECTIVE OF THE EARLY W. V. QUINE 349 CHAPTER 16 The Analytic and the Synthetic, the Necessary and the Possible, the Apriori and the Aposteriori 351 CHAPTER 17 Meaning and Holistic Verificationism 378 Suggested Further Reading 406 Index 409. (shrink)

W.V.O. Quine's doctrines of the indeterminacy of translation and the inscrutability of reference are among the most famous and influential theses in philosophy in the past fifty years. Although by no means universally accepted, the arguments for them have been widely regarded as powerful challenges to our most fundamental beliefs about meaning and reference — including the belief that many of our words have meaning and reference in the sense in which we ordinarily understand those notions, as well as beliefs (...) about the particular things meant and referred to in specific cases, such as my belief that in the past my son Brian often referred with affection to his pet rabbit Bigwig. If Quine's doctrines, and the arguments for them, are correct, then beliefs such as these cannot be accepted as true.One might expect that with consequences like these Quine's theses would widely be regarded as obviously incorrect. (shrink)

ZusammenfassungMedizinethische Entscheidungsfindungsmodelle müssen nachweisen können, weshalb die mit ihnen getroffenen Entscheidungen richtig oder zumindest „belastbar“ sind. Hierfür sind theoretische Rechtfertigungsansätze aus der Ethik unverzichtbar. Der Klinischen Ethik wird aber mitunter ein Mangel an theoretischer Fundierung vorgeworfen. Um diesem Vorwurf entgegenzutreten, soll unter Bezugnahme auf ein Projekt der Klinischen Ethik („METAP“) die ethische Unterstützung in Form der ethischen Fallbesprechung und der Ethikkonsultation mittels Prinzipienethik und Diskursethik gerechtfertigt werden. Prinzipienethik und Diskursethik können einander über das Medium der ethischen Fallbesprechung oder Ethikkonsultation fruchtbar (...) ergänzen. So können einige theoretische und praktische Schwächen der beiden Ansätze durch den jeweils anderen abgefedert werden. Die Diskursethik übernimmt bspw. die Sicherung der ethischen Gültigkeit von moralischen Entscheidungen bzw. Handlungsnormen und vermindert dadurch ein Rechtfertigungsdefizit, welches bei einem rein prinzipienorientierten Verfahren auftritt. Umgekehrt antwortet die Prinzipienethik u. a. auf Fragen der ethischen Angemessenheit und dient v. a. der adäquaten Einzelfallentscheidung. Durch die Integration des einen Ansatzes in den anderen ist eine umfassendere Rechtfertigungsleistung erzielbar als bei einem alleinigen Einsatz von Prinzipienethik oder Diskursethik. Selbst wenn einige Herausforderungen bestehen bleiben und auch das integrierte Modell moralische Dissense nicht immer verhindern kann, vermag es durch seine „doppelte“ Absicherung (Prinzipien und Diskurs) ein praktisches Vertrauen in die getroffene ethische Entscheidung zu stärken und so der Klinischen Ethik mehr „Robustheit“ zu geben, als sie bisher besitzt. (shrink)

Medizinethische Entscheidungsfindungsmodelle müssen nachweisen können, weshalb die mit ihnen getroffenen Entscheidungen richtig oder zumindest „belastbar“ sind. Hierfür sind theoretische Rechtfertigungsansätze aus der Ethik unverzichtbar. Der Klinischen Ethik wird aber mitunter ein Mangel an theoretischer Fundierung vorgeworfen. Um diesem Vorwurf entgegenzutreten, soll unter Bezugnahme auf ein Projekt der Klinischen Ethik („METAP“) die ethische Unterstützung in Form der ethischen Fallbesprechung und der Ethikkonsultation mittels Prinzipienethik und Diskursethik gerechtfertigt werden. Prinzipienethik und Diskursethik können einander über das Medium der ethischen Fallbesprechung oder Ethikkonsultation fruchtbar (...) ergänzen. So können einige theoretische und praktische Schwächen der beiden Ansätze durch den jeweils anderen abgefedert werden. Die Diskursethik übernimmt bspw. die Sicherung der ethischen Gültigkeit von moralischen Entscheidungen bzw. Handlungsnormen und vermindert dadurch ein Rechtfertigungsdefizit, welches bei einem rein prinzipienorientierten Verfahren auftritt. Umgekehrt antwortet die Prinzipienethik u. a. auf Fragen der ethischen Angemessenheit und dient v. a. der adäquaten Einzelfallentscheidung. Durch die Integration des einen Ansatzes in den anderen ist eine umfassendere Rechtfertigungsleistung erzielbar als bei einem alleinigen Einsatz von Prinzipienethik oder Diskursethik. Selbst wenn einige Herausforderungen bestehen bleiben und auch das integrierte Modell moralische Dissense nicht immer verhindern kann, vermag es durch seine „doppelte“ Absicherung (Prinzipien und Diskurs) ein praktisches Vertrauen in die getroffene ethische Entscheidung zu stärken und so der Klinischen Ethik mehr „Robustheit“ zu geben, als sie bisher besitzt. (shrink)

The aim of this article is to take the Center for Inquiry’s ((CFI) a highly influential organization in the west), mission statement to task with respect to their critique of supposed extraordinary claims through the application of Carl Sagan’s quote: “extraordinary claims require extraordinary evidence.” Specifically, those which are defensible through rational argumentation (God’s existence) i.e., in order to question whether or not they are actually promoting rigorous critical thought through the utilization of science and reason. A look will be (...) also taken into whether they are actually fostering freedom of inquiry or if they are becoming masterful at insulating themselves from any criticisms against their own respective position. This will be carried forth through the examination of the following: i) emotions and non-belief, ii) the epistemology of Carl Sagan’s quote, iii) philosophy, science and the question of God, iv) the presumption of atheism and its relation to Sagan’s quote, v) proper basicality and Sagan’s quote and vi) Jesus’ resurrection as a test case. (shrink)

Gideon Rosen: Quine and the Revival of Metaphysics: Quine's critique of Carnap's positivism and Quine's alternative account of scientific and philosophical methodology set the stage for the revival of metaphysics in the 1970s and 80s. The key ingredients in this transition were (a) Quine's insistence that theory choice in the sciences is governed by holistic, pragmatic considerations, (b) his claim that the sciences nonetheless give us reason to believe in the items they posit, and (c) his insistence that theory choice (...) in philosophy is continuous with scientific theory choice in all respects. The chapter presents Quine's account of theory choice and highlights the respects in which post‐Quinean metaphysics owes its methodological self‐conception to Quine's work. (shrink)

Creativity pervades human life. It is the mark of individuality, the vehicle of self-expression, and the engine of progress in every human endeavor. It also raises a wealth of neglected and yet evocative philosophical questions: What is the role of consciousness in the creative process? How does the audience for a work for art influence its creation? How can creativity emerge through childhood pretending? Do great works of literature give us insight into human nature? Can a computer program really be (...) creative? How do we define creativity in the first place? Is it a virtue? What is the difference between creativity in science and art? Can creativity be taught? The new essays that comprise The Philosophy of Creativity take up these and other key questions and, in doing so, illustrate the value of interdisciplinary exchange. Written by leading philosophers and psychologists involved in studying creativity, the essays integrate philosophical insights with empirical research. CONTENTS I. Introduction Introducing The Philosophy of Creativity Elliot Samuel Paul and Scott Barry Kaufman II. The Concept of Creativity 1. An Experiential Account of Creativity Bence Nanay III. Aesthetics & Philosophy of Art 2. Creativity and Insight Gregory Currie 3. The Creative Audience: Some Ways in which Readers, Viewers and/or Listeners Use their Imaginations to Engage Fictional Artworks Noël Carroll 4. The Products of Musical Creativity Christopher Peacocke IV. Ethics & Value Theory 5. Performing Oneself Owen Flanagan 6. Creativity as a Virtue of Character Matthew Kieran V. Philosophy of Mind & Cognitive Science 7. Creativity and Not So Dumb Luck Simon Blackburn 8. The Role of Imagination in Creativity Dustin Stokes 9. Creativity, Consciousness, and Free Will: Evidence from Psychology Experiments Roy F. Baumeister, Brandon J. Schmeichel, and C. Nathan DeWall 10. The Origins of Creativity Elizabeth Picciuto and Peter Carruthers 11. Creativity and Artificial Intelligence: a Contradiction in Terms? Margaret Boden VI. Philosophy of Science 12. Hierarchies of Creative Domains: Disciplinary Constraints on Blind-Variation and Selective-Retention Dean Keith Simonton VII. Philosophy of Education (& Education of Philosophy) 13. Educating for Creativity Berys Gaut 14. Philosophical Heuristics Alan Hájek. (shrink)

By the early 1970s, and continuing through 2001, David Lewis and Saul Kripke had taken over W.V.O. Quine’s leadership in metaphysics, epistemology, philosophy of language, and philosophical logic in the English-speaking world. Quine, in turn, had inherited his position in the early 1950s from Rudolf Carnap, who had been the leading logical positivist -- first in Europe, and, after 1935, in America. A renegade positivist himself, Quine eschewed apriority, necessity, and analyticity, while (for a time) adopting a holistic version of (...) verificationism. Like Carnap, he placed philosophical logic and the philosophy of science at the center of philosophy. (shrink)